Piwi proteins associate with piRNAs and functions in epigenetic programming, post-transcriptional regulation, transposon silencing, and germline development.However, it is not known whether the diverse functions of these proteins are molecularly separable.Here we report that Piwi interacts with Tudor-SN (Tudor staphylococcal nuclease, TSN) antagoni
Characteristics of treatment naive chronic hepatitis B in Bangladesh: Younger populations are more affected; HBeAg-negatives are more advanced
Background/Aim: Bangladesh is a densely populated country with intermediate endemicity for chronic hepatitis B (CHB).The aim of the present study was to evaluate the biochemical, virological and histological character of CHB patients and to examine 6 Piece Queen Bedroom the relationship between these indices.Materials and Methods: One thousand and
Gating of a pH-sensitive K(2P) potassium channel by an electrostatic effect of basic sensor residues on the selectivity filter.
K(+) channels share common selectivity characteristics but exhibit a wide diversity in how they are gated open.Leak K(2P) K(+) channels TASK-2, TALK-1 and TALK-2 are gated open by GINGER PWD extracellular alkalinization.The mechanism for this alkalinization-dependent gating has been proposed to be the neutralization of the side chain of a single ar
An Analysis of Road Pavement Collapses and Traffic Safety Hazards Resulting From Leaky Sewers
In this paper, road pavement collapses resulting from sewer leakage are divided into six categories: negligible, marginal, considerable, serious, very serious and catastrophic, with the categorization being based on two criteria, both related to traffic safety, i.e., the number of fatalities caused by sinkholes, and the extent of the road pavement